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Encompassing Dr Baranski's 20 years of experience in the filed of abdominal organ donation, this book is a comprehensive step-by-step guide to the field, with many colour photographs and clear drawings to aid the reader. The text concisely demonstrates the many difficult steps in the organ procurement process, also highlighting the major potential pitfalls and common surgical mistakes that have arisen during the author's extensive career. The success of organ transplantation starts with the optimal medical and surgical treatment of the donor as without good organ harvesting, there is a high mortality incidence in the patients on the waiting list and thus less space for new patients. Organ procurement is therefore now recognized as an essential part of organ transplantation. In most donors, the surgical procedure can be challenging for an inexperienced surgeon and so often a detailed walkthrough is required to prepare for the operation. This part of transplant surgery is critically important as inadequate preservation or surgical injury at this stage can lead to complete organ damage or to serious complications in the recipient. At present, most multi-organ donor (MOD) procurement procedures are performed by a local surgical team, which is not necessarily the same team as the one responsible for the transplantation. The accepting center therefore has to rely on the expertise and skills of the procurement team, meaning that adequate training and a standardization of the surgical techniques is of vital importance. This title is a useful pocket guide for practicing surgeons or senior residents participating in organ procurement teams, wishing to learn abdominal organ procurement. The high illustrative content offers great worth as a step-by-step walkthrough, with clear diagrams further supplementing the text to provide the most detailed handbook available on abdominal transplantation.

Orthopaedics. Traumatology. Plastic surgery --- Surgery --- transplantaties

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Skin Cancer after Organ Transplantation presents the state-of-the-art knowledge of cutaneous malignancies following organ transplantation. The life promoting and life enhancing benefits of solid organ transplantation is a major medical advance, but at the cost of the life-long immunosuppression needed to prevent rejection of the donated organ. This induction and maintenance of impaired immunological surveillance is paralleled by a significant increase in the incidence of specific cancers, of which skin cancers are highest. The book is divided into four sections, providing a basic overview on transplantation medicine, different immunosuppressive agents and their impact on the skin's immune system, epidemiology and pathophysiology of skin cancer, applicable prophylaxis and therapeutic measures. 1. Transplant medicine: Addresses the immunological background of organ transplantation, immunosuppression and the impact on the cutaneous immunosurveillance. Different immunosuppressive drugs are presented and their interaction with mechanisms of the cutaneous immunosurveillance against skin cancer, are discussed. 2. Post-transplant skin malignancies: Explores the pathogenesis of transplant skin cancer, epidemiological patterns in different geographical regions, clinical and histological features, etiological factors and molecular events in skin cancer induction and progression, i.e., photocarcinogenesis and UV-induced immunosuppression, and oncogenic viruses like human papillomavirus and human herpesvirus, type 8. 3. Specific skin cancers: Focuses on specific skin cancers in organ transplant recipients, especially the most predominant types, like squamous cell carcinoma, its precursor actinic keratoses, and basal cell carcinoma, but also malignant melanoma, Kaposi's sarcoma, cutaneous T-cell lymphoma and other, more rare skin malignancies. 4. Prophylaxis and therapies: Experts in the field recommend management strategies for preventing and treating transplant skin cancer, with an emphasis on a multidisciplinary approach. As scientists and clinicians strive together to develop effective chemopreventative agents in the face of this accelerated carcinogenesis, there is a real opportunity for advances in the treatment of transplant skin malignancies to translate into reduced skin cancer in the general population. "Immunosuppression is an essential component of organ transplantation. Unfortunately, the risk of skin cancer is drastically increased in this setting. Distinguished investigators discuss the cause and therapeutic strategies involving the spectrum of cutaneous malignancies associated with immunosuppression." Steven T. Rosen, M.D., Series Editor

Oncology. Neoplasms --- Pathological dermatology --- Surgery --- huidkanker --- dermatologie --- oncologie --- chirurgie --- transplantaties

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In Klinische Immunologie wordt het complexe immuunsysteem van de mens helder en overzichtelijk uiteengezet.

Immunologie is de studie van het immuunsysteem. Het immuunsysteem is uitermate dynamisch en ingewikkeld en heeft als belangrijkste doel het lichaam te beschermen tegen infecties door alle mogelijke micro-organismen en parasieten. Veel verschillende celtypen en moleculen werken samen om zo'n infectie te bestrijden. Het immuunsysteem is altijd actief, gelukkig veelal zonder dat we het merken. Immunologie is een modern vakgebied dat volop in beweging is. Veel ziekten en aandoeningen hebben een immunologische component en tal van nieuwe therapieën zijn gestoeld op immunologische werkingsprincipes. 

In Klinische Immunologie wordt het complexe immuunsysteem van de mens helder en overzichtelijk uiteengezet.In dit boek staan de meer klinische aspecten van het immuunsysteem centraal. Onderwerpen als immuundeficiëntie, overgevoeligheidsreacties, afstoting bij transplantaties en vaccinaties worden daarin behandeld. De voor de klinische praktijk belangrijke stoornissen van het immuunsysteem die het gevolg kunnen zijn van voeding, stress en genotsmiddelen, worden besproken in een eigen hoofdstuk, 'Verworven stoornissen van het immuunsysteem'. 

De nadruk in deze uitgave ligt op de klinische praktijk. Met behulp van diverse aansprekende klinische voorbeelden en alledaagse casuïstiek behandelen de auteurs de eigenschappen en functies van honderden moleculen en cellen (zowel de hoofdrolspelers als de figuranten). 

Immunologie is geschreven in het Nederlands en de behandelde ziekten, getallen en statistieken zijn gebaseerd op de Nederlandse situatie. De auteurs zijn deelspecialisten en behoren tot de top van de Nederlandse wetenschap op het gebied van immunologie. Door de leesbaarheid en duidelijke structuur van de tekst, de overzichtelijke tekeningen, illustraties en foto's wordt de ingewikkelde materie zo helder mogelijk aangeboden.


vaccins --- besmettelijke ziekten --- allergieën --- allergies --- History of chemistry --- Allergy --- immunologie --- Immunology. Immunopathology --- transplantaties --- vaccinatie

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Human biochemistry --- Orthopaedics. Traumatology. Plastic surgery --- Surgery --- medische biochemie --- biochemie --- chirurgie --- transplantaties

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In this second edition of Nuclear Hepatology: A Textbook of Hepatobiliary Disease, the authors build on the success of the first edition by revising the contents so as to encompass all of the most recent developments in the field. The result is a comprehensive, up-to-date book that will serve as a ready reference and a clinical and procedural guide for all who care for patients with hepatobiliary diseases. The authors, both of whom are nuclear medicine physicians, present nuclear hepatobiliary imaging techniques in the context of the many other possible diagnostic studies, thereby acquainting the reader with the role of these procedures. The book is organized into 13 chapters. Introductory chapters cover the morphology and microstructure of the hepatobiliary system and discuss liver and spleen function. The important imaging agents are then reviewed in turn. Subsequent chapters describe the imaging of liver and spleen morphology and procedures used to quantify hepatobiliary function, with particular attention to the gallbladder and the sphincter of Oddi. The remaining chapters address intra- and extrahepatic cholestasis, diseases of the gallbladder, biliary dyskinesia, hepatobiliary diseases in infants and children, liver malignancies, and liver transplantation. Throughout, care is taken to maintain a clear clinical focus and to emphasize the importance of integrating information on morphology and quantitative physiology as the basis for diagnosis. Each of the chapters is well illustrated and concludes with a detailed reference list. This book will prove invaluable not only to nuclear medicine physicians but also to practitioners of radiology, internal medicine, pediatrics, gastroenterology, hepatology, primary care, general surgery, and liver transplantation surgery.

Nuclear physics --- Physical methods for diagnosis --- Gastroenterology --- Orthopaedics. Traumatology. Plastic surgery --- Surgery --- gastro-enterologie --- leverziekten --- transplantaties --- radiologie --- medische beeldvorming